Department of agriculture agricultural research service. Structures of new sesquiterpenes and hepatoprotective. Antiviral activity of dicrocephala integrifolia kuntze against herpes simplex. Dichrocephala integrifolia asteraceae is a small herb widely distributed in many countries in asia, africa, and the middle east. In order to verify if this medicinal plant possesses active compounds capable of inhibiting the embryonation and hatching of eggs or to. Dichrocephala integrifolia asteraceae is commonly used in the folk medicine in cameroon to treat various ailments including headaches, jaundice, filariasis, neuritis and childrens night agitation. The genus dichrocephala is in the family compositae in the major group angiosperms flowering plants. Dichrocephala integrifolia is an erect or spreading, aromatilc annual plant growing 20 60cm tall, occasionally to 100cm. Chemical investigation of triterpenoids from dichrocephala benthamii. To screen the major phytochemical constituents and evaluate antibacterial activity tests of leaf extracts of dichrocephala integrifolia l.
Schulz tsn 565718, published in 1903, is an isonym of brassica integrifolia h. Ethnomedicine of the kagera region, north western tanzania. A new name and neotypification for hippia integrifolia. Their absolute stereostructures were determined on the basis of chemical and physicochemical evidence. In vitro anthelminthic efficacy of dichrocephala integrifolia asteraceae extracts on the gastrointestinal nematode parasite of mice. Chemical constituents of dichrocephala integrifolia. The kagera region has a magnificent culture of herbalism.
Files are available under licenses specified on their description page. Dichrocephala is a genus of flowering plants in the sunflower family, native to tropical africa. This study, the second on an ongoing series, reports on the medicinal plant species used in katoro ward, bukoba district, and tries to use. Neuropharmacology study was done by open field and hole cross test whereas acetic acid writhing test and formalin induced pain. The triterpenoids of dichrocephala benthamii were investigated by means of silica gel, sephadex lh20 and semipreparative hplc. Jun 26, 2006 three new pseudoguaianetype sesquiterpenes, dichrocepholides ac, and two new pseudoguaianetype sesquiterpene dimers, dichrocepholides d and e, were isolated from the aerial part of dichrocephala integrifolia. Kuntze asteraceae in a mice model of dgalactoseinduced oxidative stress and accelerated aging. Heliotropium indicum, commonly known as indian heliotrope, is an annual, hirsute plant that is a common weed in waste places and settled areas. Manzanita, a spanish word which translates to little apple, named for its green and red berries, is one of the most attractive and recognizable members of the california flora attractive container gardens. Four new dolabellanetype diterpene alkaloids, nigellamines a1 1, a2 2, b1 3, and b2 4, were isolated from the seeds of nigella sativa. Article pdf available in bothalia african biodiversity and conservation 431. Anthelminthic activity of moringa oleifera leaf extracts. The plant list includes 36 scientific plant names of species rank for the genus dichrocephala. The results of this study reveal that dichrocephala integrifolia is a medicinal plant that protects the brain against monosodium glutamatemediated.
Datasets containing persea americana, macadamia integrifolia and mangifera indica raw trinity transcriptome assemblies, unigenes, and functional annotation files were deposited in. The medicinal plants of katoro ward, bukoba district. The role of traditional healers in tooth extractions in lekie. Nigellamines a1 1, b1 3, and b2 4 were found to show potent lipid metabolism promoting activity in primary cultured mouse hepatocytes, and. The stereostructures of the new sesquiterpenes were determined on the basis of chemical and physicochemical evidence. Pdf ethnomedicine of the kagera region, north western. While the haya tribe dominates the region, there is a lot of knowledge exchange with the neighboring tribes like the rukiga and banyankore of uganda, the tutsi and the hutu of rwanda and burundi who have all intermarried overtime bringing together an impressive culture of herbal centered traditional medicine. When several references are cited, they may give conflicting information on the status. Kuntze asteraceae leaves aqueous extract prevents ethano linduced liver damage in rats 1ngueguim tsofack florence, 1mbatchou adolphe, 2donfack jean hubert, 1dzeufiet djomeni desire paul, 1gounoue kamkumo raceline, 1djouwoug noussi clarice, 1kamtchouing pierre and 1dimotheophile. Chemical investigation of triterpenoids from dichrocephala.
The present study investigates the knowledge and practices of traditional healers regarding tooth extraction and the management of its. Kuntze, is a sparingly branched annual herb, which is widely distributed in african, middle eastern, and asian countries. Anxiolytic and sedative activities of aqueous leaf extract. Dichrocephala integrifolia did not increased or impaired the locomotion of scopolamine treated mice in the y maze figure 1b effects of d. Dichrocephala chrysanthemifolia is a straggling, aromatic, branched, annual plant growing up to 100cm tall332. The dynamic interethnic interactions of different people from the surrounding countries constitute a rich reservoir of herbal based healing practices. Kuntze is an accepted name this name is the accepted name of a species in the genus dichrocephala family compositae. Haemonchus contortus is a bloodsucking abomasal helminth of small ruminants responsible for major economic losses to small farmers worldwide. Widespread resistance to synthetic anthelminthics has stimulated a need for alternative strategies of parasite control, among which is the use of medicinal plants with natural anthelminthic properties. By the 21st century, african neuroscience expanded to other areas of basic and clinical.
Dichrocephala integrifolia root and flower extracts are effective in the control. It is widely used in native medicine in tamil nadu, india. Dichrocephone b 2 contains a new ring system formed by. The plant list includes a further 20 scientific plant names of infraspecific rank for the genus dichrocephala.
In addition, the principal constituents were found to. In addition, the extract and its principal sesquiterpene constituent. Plant atlas web site overview march 2017 san diego county, with natural environments ranging from sea coast, up through foothills and mountains, and down to the desert, is a hotbed of botanical diversity. It has been the subject of in vitro studies that have noted its anticancer, antimicrobial, antiinflammatory and. Avh is a collaborative project of the state, commonwealth and territory herbaria, developed under the auspices of the council of heads of australasian herbaria chah, representing the major australian collections. In vitro anthelminthic efficacy of dichrocephala integrifolia ncbi. Dichrocephala is a genus of flowering plants in the sunflower family, native to tropical africa and southern asia species. Philippine herbal medicine an illustrated compilation of philippine medicinal plants by dr godofredo umali stuart with botanical information, chemical properties, folkloric uses and medicinal research studies. The pdf file you selected should load here if your web browser has a pdf reader plugin installed for example, a recent version of adobe acrobat reader if you would like more information about how to print, save, and work with pdfs, highwire press provides a helpful frequently asked questions about pdfs. Leaves lyratepinnatifid, 26 cm long, 14 cm wide, lobes toothed, sometimes lateral lobes absent, surfaces sparsely hairy.
Clarke, together with the known compound syringenin isovalerate 5. The kagera region of north western tanzania has a rich culture of traditional medicine use and practices. Their structures were elucidated on the basis of spectroscopic analysis. The asteraceae plant, dichrocephala integrifolia l. In addition, the extract and its principal sesquiterpene constituent, parthenin, showed. In vitro anthelminthic efficacy of dichrocephala integrifolia. Grangeinae in guatemala, an exotic genus and species new to. Dichrocephala integrifolia asteraceae is commonly used in the folk medicine in cameroon to treat various ailments including headaches.
As shown in figure 2a, there was a significant difference among groups concerning the initial transfer latency. We do not intend the plant list to be complete for names of infraspecific rank. Dichrocephala integrifolia, dichrocephala latifolia lam. Nootropic and neuroprotective effects of dichrocephala. Composition of the essential oil from leaves and flowers of dichrocephala integrifolia. Preliminary phytochemical screening and evaluation of.
Reference to the brain and nervous system is found in 5000yearold ancient egyptian writings on medical procedures russell, 2017. The role of traditional healers in tooth extractions in lekie division, cameroon journal of ethnobiology and ethnomedicine, may 2011 ashu m agbor, sudeshni naidoo, awono m mbia. It often branches freely at the base, though can a,so be unbranched, and forms new roots at the leaf nodes266. Kuentze asteraceae is an annual herbaceous plant and distributes in tropical and subtropical asia and africa boufford et al. The distribution in this summary table is based on all the information available. Novel dolabellanetype diterpene alkaloids with lipid. See status, confidence level, source for definitions.
Dichrocephones a and b, two cytotoxic sesquiterpenoids. Many species of the genus dichrocephala are used as folk medicines for ulcer, fever, hypertension, and pneumonia. Antibacterial, antifungal, antiviral, and anthelmintic. This page was last edited on 1 february 2015, at 11. It has been the subject of in vitro studies that have noted its anticancer, antimicrobial, antiinflammatory and antioxydant activities 7. All structured data from the file and property namespaces is available under the. The largest proportion of medicinal plants collected belonged to the family asteraceae 21%, followed by fabaceae 12. Dichrocephones a 1 and b 2, two new modhephane sesquiterpenoids containing the key core skeleton as that of modhephane sesquiterpenoids rarely encountered in nature were isolated from dichrocephala benthamii. For more multimedia, look at dichrocephala integrifolia on wikimedia commons.
Sinapyl alcohol derivatives from the liposoluble part of. The role of traditional healers in tooth extractions in. The record derives from tica data supplied on 20120211 which reports it as an accepted name record a99cc91803c74b2d91bd7fe22a863580 with original publication details. A new name and neotypification for hippia integrifolia less. Three new pseudoguaianetype sesquiterpenes, dichrocepholides ac, and two new pseudoguaianetype sesquiterpene dimers, dichrocepholides d and e, were isolated from the aerial part of dichrocephala integrifolia. Four new sinapyl alcohol derivatives dichrocephols ad compounds 14 were isolated from the liposoluble part of the whole herb of dichrocephala benthamii c. Antioxidant activities of dichrocephala integrifolia linn. Pdf on nov 1, 2017, kouemou emegan nadege and others published antioxidant properties of dichrocephala integrifolia asteraceae in a mouse model of monosodium glutamateinduced neurotoxicity. The pdf file you selected should load here if your web browser has a pdf reader plugin installed for example, a recent version of adobe acrobat reader if you would like more information about how to print, save, and work with pdfs, highwire press provides a helpful frequently asked questions about pdfs alternatively, you can download the pdf file directly to your computer, from where it. Nov 21, 2017 dichrocephala integrifolia is a plant of the family asteraceae that is widely used in traditional medicine in cameroon to treat and prevent dementia and alzheimer disease ngueguim et al. Pdf antioxidant activities of dichrocephala integrifolia. Research was carried out in konta special woreda district. To evaluate the ovicidal and larvicidal activities of aqueous and ethanolic extracts of leaves of dichrocephala integrifolia d. Weed science publishes research related to weed science in agricultural systems, such as herbicide resistance, weed control tools, chemistry, and genetics.
Anxiolytic and sedative activities of aqueous leaf extract of. For more multimedia, look at dichrocephala on wikimedia commons. Dicoma kirkii m echinops hoehnelii n, k, m erigeron karvinskianus dc. All structured data from the file and property namespaces is available under the creative commons cc0 license. In the 20th century, modern neuroscience research began in africa on potential treatments for epilepsy, infectious disease, nutritional neuropathies, stroke, and tumours. Traditional healers th use herbs and crude unsterilized instruments and tools for the tooth extraction procedure. An ethnobotanical study of medicinal plants used by local. Dichrocephala chrysanthemifolia useful tropical plants. Six new sesquiterpenes, cyperusols a1 1, a2 2, b1 3, b2 4, c 5, and d 6, together with two monoterpenes and sesquiterpenes were isolated from an egyptian herbal medicine, the whole plants of cyperus longus. Dichrocephala integrifolia in the germplasm resources information network grin, u.
It often branches freely at the base, though can a,so be unbranched, and forms new roots at the leaf nodes. Dichrocephala integrifolia in global plants on jstor. The main source of these plants in terms of number of species were trees 30. Oyen and nguyen xuan dung, prosea foundation, backhuys publishers, leiden, the netherlands, 1999. Their stereostructures were determined on the basis of chemical and physicochemical evidence. Therefore, this research was conducted to investigate medicinal plants of the konta people and to document the local knowledge before environmental and cultural changes deplete the resources. Preliminary pharmacological studies were performed on the methanolic extract of premna integrifolia mepi bark to investigate neuropharmacological, analgesic, and antiinflammatory activities. Anxiolytic and sedative activities of aqueous leaf extract of dichrocephala integrifolia asteraceae in mice.
Their absolute configurations were established by the method of alkaline hydrohysis. Traditional medicine plays a great role in combating this disease. Dichrocephala integrifolia root and flower extracts are effective in the control of human herpes simplex virus. Indian heliotrope is an annual, erect, branched plant that can grow to a height of about 1550 cm 5. Article in chinese song b, zhang qb, wang mh, tian xh, sun hl, zhang fb, zou zm, ding g. Stems solitary or fascicled, robust, rarely slender, branched, sparsely to densely white villous or pubescent. Antioxidant properties of dichrocephala integrifolia. Pseudoguaianetype sesquiterpenes and inhibitors on nitric. The composition of the essential oil from the leaves and. The extraction of the teeth by traditional healers in cameroon is an established cultural practice in the central region of the cameroon. Media in category dichrocephala integrifolia the following 2 files are in this category, out of 2 total.